References in Leptospirosis in American Samoa 2010: Epidemiology, environmental drivers, and the management of emergence - GCIS

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reference : Leptospirosis in American Samoa 2010: Epidemiology, environmental drivers, and the management of emergence

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Leptospirosis in American Samoa 2010: Epidemiology, environmental drivers, and the management of emergence

Bibliographic fields
reftype	Journal Article
Abstract	Leptospirosis has recently been reported as an emerging disease worldwide, and a seroprevalence study was undertaken in American Samoa to better understand the drivers of transmission. Antibodies indicative of previous exposure to leptospirosis were found in 15.5% of 807 participants, predominantly against three serovars that were not previously known to occur in American Samoa. Questionnaires and geographic information systems data were used to assess behavioral factors and environmental determinants of disease transmission, and logistic regression was used to identify factors associated with infection. Many statistically significant factors were consistent with previous studies, but we also showed a significant association with living at lower altitudes (odds ratio [OR] = 1.53, 95% confidence interval [CI]: 1.03â2.28), and having higher numbers of piggeries around the home (OR = 2.63, 95% CI: 1.52â4.40). Our findings support a multifaceted approach to combating the emergence of leptospirosis, including modification of individual behavior, but importantly also managing the evolving environmental drivers of risk.
Author	Lau, Colleen L.; Dobson, Annette J.; Smythe, Lee D.; Fearnley, Emily J.; Skelly, Chris; Clements, Archie C. A.; Craig, Scott B.; Fuimaono, Saipale D.; Weinstein, Philip
DOI	10.4269/ajtmh.2012.11-0398
Date	February 1, 2012
ISSN	0002-9637
Issue	2
Journal	The American Journal of Tropical Medicine and Hygiene
Pages	309-319
Title	Leptospirosis in American Samoa 2010: Epidemiology, environmental drivers, and the management of emergence
Volume	86
Year	2012

Bibliographic identifiers
.reference_type	0
_record_number	19032
_uuid	dcfd936b-edfa-4da1-84a1-8fab067fff87